{"id":1793,"date":"2019-03-11T22:29:00","date_gmt":"2019-03-11T22:29:00","guid":{"rendered":"https:\/\/www.naturaltreatmentforhypertension.com\/blog\/?p=1793"},"modified":"2019-03-11T22:29:00","modified_gmt":"2019-03-11T22:29:00","slug":"portal-hypertension","status":"publish","type":"post","link":"https:\/\/www.naturaltreatmentforhypertension.com\/blog\/portal-hypertension\/","title":{"rendered":"Portal Hypertension"},"content":{"rendered":"<p><span style=\"color : #666; font-weight:normal; text-decoration:none;\"><\/p>\n<p>Signs and symptoms<\/p>\n<p>* Jaundice<\/p>\n<p>* History of blood transfusion<\/p>\n<p>* Intravenous drug abuse<\/p>\n<p>* History of alcohol consumption<\/p>\n<p>* Pruritus<\/p>\n<p>* Hematemesis<\/p>\n<p>* Melena<\/p>\n<p>* Lethargy<\/p>\n<p>* Increased irritability<\/p>\n<p>* Altered sleep patterns<\/p>\n<p>* Increased abdominal girth due to ascites<\/p>\n<p>* Hematochezia<\/p>\n<p>* Abdominal pain<\/p>\n<p>* Fever<\/p>\n<p>Signs of port systemic collateral formation<\/p>\n<p>* Dilated veins in the anterior abdominal wall<\/p>\n<p>* Venous pattern on the flanks<\/p>\n<p>* Caput medusa<\/p>\n<p>* Rectal hemorrhoids<\/p>\n<p>* Ascites<\/p>\n<p>* Paraumblical hernia<\/p>\n<p> Signs of liver disease<\/p>\n<p>* Ascites<\/p>\n<p>* Jaundice<\/p>\n<p>* Spider nevi<\/p>\n<p>* Gynecomastia<\/p>\n<p>* Dupuytren&#8217;s contracture<\/p>\n<p>* Muscle wasting<\/p>\n<p>* Palmar erythema<\/p>\n<p>* Asterixis<\/p>\n<p>* Testicular atrophy<\/p>\n<p>* Splenomegaly<\/p>\n<p>Causes<\/p>\n<p>Prehepatic<\/p>\n<p>* Portal vein thrombosis<\/p>\n<p>* Splenic vein thrombosis<\/p>\n<p>* Extrinsic compression by tumor<\/p>\n<p>* Arteriovenous fistula<\/p>\n<p>Intrahepatic presinusoidal and\/ or postsinusoidal<\/p>\n<p>* Hepatic cirrhosis<\/p>\n<p>* Acute alcoholic hepatitis<\/p>\n<p>* Primary biliary cirrhosis<\/p>\n<p>* Congenital hepatic fibrosis<\/p>\n<p>* Vitamin A toxicity<\/p>\n<p>* Budd chiari syndrome<\/p>\n<p>* Pelisosis hepatitis<\/p>\n<p>Intrahepatic, predominantly presinusoidal<\/p>\n<p>* Shistosomiasis<\/p>\n<p>* Primary biliary cirrhosis<\/p>\n<p>* Nodular regenerative hyperplasia<\/p>\n<p>* Polycystic disease<\/p>\n<p>* Hepatic metastasis<\/p>\n<p>* Granulomatous disease (sarcoidosis and tuberculosis)<\/p>\n<p>Treatment<\/p>\n<p>Emergency treatment<\/p>\n<p>* Each episode of variceal bleeding is associated with 30% mortality fever.<\/p>\n<p>* Initial resuscitation with replacement of blood volume loss by packed or whole red blood cells or plasma expanders.<\/p>\n<p>* Avoid intravascular volume and variceal overexpansion to prevent re bleeding.<\/p>\n<p>* Prophylactic antibiotic use to decrease the rate of bacterial infections.<\/p>\n<p>Pharmacotherapy<\/p>\n<p>* Somatostatin- is an endogenous hormone that decreases the portal blood flow by vasoconstriction.<\/p>\n<p>* Octreotide- it&#8217;s an analogue of somatostatin, also effective in reducing the complications of variceal bleeding after emergency sclerotherapy or variceal ligation<\/p>\n<p>* Vasopressin- Most potent vasoconstrictor has more side effects.<\/p>\n<p>* Terlipressin- has fewer adverse effects than vasopressin.<\/p>\n<p>Endoscopic therapy<\/p>\n<p>* Endoscopic therapy has the advantage of allowing specific therapy at the time of diagnosis.<\/p>\n<p>* >80% of hemostasis can be achieved.<\/p>\n<p>* Endoscopic injection sclerotherapy involves injecting sclerosant solution like sodium morrhuate, sodium tetradecyl sulfate, and ethanolamine oleate into the bleeding veins.<\/p>\n<p>Endoscopic variceal ligation<\/p>\n<p>Other interventions<\/p>\n<p>* Balloon tube tamponade<\/p>\n<p>* Minnesota tube<\/p>\n<p>Primary prophylaxis<\/p>\n<p>* Beta blockers- Propranolol and Nadolol<\/p>\n<p>* Vasodilators- Isosorbide mononitrate<\/p>\n<p>* Combination therapy- Propranolol and Isosorbide mononitrate<\/p>\n<p>* Prophylactic sclerotherapy<\/p>\n<p>* Prophylactic endoscopic variceal ligation<\/p>\n<p>Surgical care<\/p>\n<p>Decompressive shunts<\/p>\n<p>* Total portal systemic shunts<\/p>\n<p>* Partial portal systemic shunts<\/p>\n<p>* Selective shunts<\/p>\n<p>Devascularization procedures<\/p>\n<p>* Splenectomy<\/p>\n<p>* Liver transplantation<\/p>\n<p>\t\t\t\t\t\t\t\t\t\t\t<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Signs and symptoms * Jaundice * History of blood transfusion * Intravenous drug abuse * History of alcohol consumption * Pruritus * Hematemesis * Melena * Lethargy * Increased irritability * Altered sleep patterns * Increased abdominal girth due to ascites * Hematochezia * Abdominal pain * Fever Signs of port systemic collateral formation * [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[3],"tags":[2915,11506,7337,4882,11505,7320,2914,2912,2911,11504,630,2913],"class_list":["post-1793","post","type-post","status-publish","format-standard","hentry","category-high-blood-pressure","tag-abuse-history","tag-ascites-paraumblical","tag-balloon","tag-bleeding","tag-hematochezia-abdominal","tag-hepatic","tag-hepatic-cirrhosis","tag-history-of-blood-transfusion","tag-initial-resuscitation","tag-jaundice-history","tag-portal-hypertension","tag-tuberculosis-treatment"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.4 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Portal Hypertension<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" 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